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DementiaToday posts scientific news and professional views on Alzheimer’s disease and other dementias from the global research community. We hope to promote better health care through education, provide support to caregivers and loved ones who live with these diseases everyday, and thank the many individuals around the world who are dedicated to neurological research and […]

IN THE SPOTLIGHT

Cancer Drug That Might Slow Parkinson’s, Alzheimer’s Headed For Bigger Tests

(NPR.org) Scientists are hoping that a single drug can treat two devastating brain diseases: Parkinson's and Alzheimer's. The drug is nilotinib, which is approved to treat a form of leukemia. In late 2015, researchers at Georgetown University Medical Center found that small doses of the drug appeared to help a handful of people with Parkinson's disease and a related form of dementia. They'd … [Read More...]

DAILY NEWS

‘Jumping Genes’ May Set Stage for Brain Cell Death in Alzheimer’s, Other Diseases

(Duke University) The latest round of failed drug trials for Alzheimer’s has researchers questioning the reigning approach to battling the disease, which focuses on preventing a sticky protein called amyloid from building up in the brain. Duke University scientists have identified a mechanism in the molecular machinery of the cell that could help explain how neurons begin to falter in the initial … [Read More...]

Mayo Clinic Publishes Genetic Screen for Alzheimer’s in African-Americans

(Journal of Alzheimer's Disease) A Mayo Clinic research team has found a new gene mutation that may be a risk factor for late-onset Alzheimer’s disease in African-Americans. This is the first time this gene has been implicated in the development of this disease in this population. Alzheimer’s disease has been understudied in African-Americans, despite the fact that the disease is twice as … [Read More...]

Autoimmune Conditions and Dementia: What’s the Link?

(MedicalNewsToday) A recent large-scale study concludes that individuals with autoimmune conditions may have an increased risk of developing dementia later in life. Although the effect size is relatively small, if the findings are replicated, they will have important clinical implications. Dementias are a range of conditions, the most prevalent of which is Alzheimer's. They are characterized by … [Read More...]

New Approach to Treating Alzheimer’s Disease

(Ulsan National Institute of Science and Technology) Alzheimer’s disease (AD) is one of the most common form of dementia. In search for new drugs for AD, the research team, led by Professor Mi Hee Lim of Natural Science at UNIST has developed a metal-based substance that works like a pair of genetic scissors to cut out amyloid-β (Aβ), the hallmark protein of AD. The study has been featured on … [Read More...]

Alzheimer’s Disease and Alternative Treatments

(Alzheimer's Association) A growing number of herbal remedies, dietary supplements and "medical foods" are promoted as memory enhancers or treatments to delay or prevent Alzheimer’s disease and related dementias. Claims about the safety and effectiveness of these products, however, are based largely on testimonials, tradition and a rather small body of scientific research. The rigorous scientific … [Read More...]

CAREGIVER’S CORNER

Answers to Tax Questions Caregivers Ask Most

(AgingCare.com) With tax time comes rules, exceptions, exemptions, requirements – and lots of confusion. AgingCare has gathered a list of frequently asked questions that caregivers ask most, with responses from the IRS website. Q: Can I claim my elderly parent who lives in my home as a dependent on my tax return? A: You may claim your parent as a dependent if the following tests are met: … [Read More...]

Helping Family and Friends Understand Alzheimer’s Disease

(National Institutes of Health) When you learn that someone has Alzheimer’s disease, you may wonder when and how to tell your family and friends. You may be worried about how others will react to or treat the person. Realize that family and friends often sense that something is wrong before they are told. Alzheimer’s disease is hard to keep secret. There’s no single right way to tell others … [Read More...]

Alzheimer’s Disease and Planning for Care

(UCSF Memory and Aging Center) The first step in planning care is getting an accurate diagnosis. Diagnosis Seek out a dementia clinic at a university hospital or ask your doctor to refer you to a neurologist with expertise in dementia and neurodegenerative disease. Educate Yourself Learn what you can about dementia and neurodegenerative disease. Understanding what is happening to your loved … [Read More...]

Alzheimer’s Disease and When to Stop Driving

(Mayo Clinic) If your loved one has Alzheimer's, he or she may not be safe on the road. Explain the risks — then provide other ways to get around. Driving is a powerful symbol of competence and independence, besides being a routine part of adult life. But the focused concentration and quick reaction time needed for safe driving tends to decline with age. Alzheimer's disease accelerates this … [Read More...]

SCIENCE CORNER

The Discovery of Alzheimer’s Disease

Dialogues Clin Neurosci. 2003 Mar; 5(1): 101–108. The discovery of Alzheimer's disease Hanns Hippius, MD* Hanns Hippius, Psychiatrische Klinik der LMU, Munich, Germany; Gabriele Neundörfer, MD Gabriele Neundörfer, Psychiatrische Klinik der LMU, Munich, Germany; Abstract On Novembers, 1306, a clinical psychiatrist and neuroanatomist, Alois … [Read More...]

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

Mayo Clin Proc. 2011 Sep;86(9):876-84. doi: 10.4065/mcp.2011.0252. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Ahlskog JE1, Geda YE, Graff-Radford NR, Petersen RC. Abstract A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive … [Read More...]

Prolonged Sleep Duration as Marker of Early Neurodegeneration Predicting Dementia

Neurology. 2017 Feb 22. pii: 10.1212/WNL.0000000000003732. doi:[Epub ahead of print] Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Westwood AJ1, Beiser A1, Jain N1, Himali JJ1, DeCarli C1, Auerbach SH1, Pase MP2, Seshadri S2. Abstract OBJECTIVE To evaluate the association between sleep … [Read More...]

Vitamin E for Alzheimer’s Dementia and Mild Cognitive Impairment

Cochrane Database Syst Rev. 2017 Jan 27;1:CD002854. doi: 10.1002/14651858.CD002854.pub4. [Epub ahead of print] Vitamin E for Alzheimer's dementia and mild cognitive impairment. Farina N1, Llewellyn D2, Isaac MG3, Tabet N1. Abstract Background Vitamin E occurs naturally in the diet. It has several biological activities, including … [Read More...]