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DementiaToday posts scientific news and professional views on Alzheimer’s disease and other dementias from the global research community. We hope to promote better health care through education, provide support to caregivers and loved ones who live with these diseases everyday, and thank the many individuals around the world who are dedicated to neurological research and […]

IN THE SPOTLIGHT

Alzheimer’s Falls More Heavily on Women Than on Men

(Scientific American) Distinct biological and genetic factors may shape how it progresses in women—and understanding them could be crucial to prevention, diagnosis and treatment. For more than 25 years, Mary Read was a successful nurse in Lititz, Pennsylvania. But in 2010, at the age of 50, she started having trouble with her memory and thinking, making it difficult for her to complete routine … [Read More...]

DAILY NEWS

Very High Levels of Aluminium in Brain Tissue in Familial Alzheimer’s Disease

(MedicalNewsToday) There has been a strong link between human exposure to aluminium and the incidence of Alzheimer's disease for half a century or more. The aluminium content of brain tissue in late-onset or sporadic Alzheimer's disease is significantly higher than is found in age-matched controls. Even higher levels of aluminium have been found in individuals, diagnosed with an … [Read More...]

Investigational New Drug for Alzheimer’s Scheduled for First Study in Humans

(Vanderbilt University Medical Center) Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration (FDA) that testing in humans may proceed for an investigational new drug for Alzheimer’s disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center. It is relatively uncharted territory for … [Read More...]

Regular Exercise Changes the Brain to Improve Memory, Thinking Skills

(Harvard Health Publications) There are plenty of good reasons to be physically active. Big ones include reducing the odds of developing heart disease, stroke, and diabetes. Maybe you want to lose weight, lower your blood pressure, prevent depression, or just look better. Here’s another one, which especially applies to those of us (including me) experiencing the brain fog that comes with age: … [Read More...]

Are Cholesterol-Lowering Statins Associated with Reduced Alzheimer Risk?

(The JAMA Network Journals) An analysis of Medicare data suggests that high use of cholesterol-lowering statins was associated with a reduced risk for Alzheimer disease but that reduction in risk varied by type of statin and race/ethnicity, findings that must be confirmed in clinical trials, according to a new article published online by JAMA Neurology. Previous research has suggested a … [Read More...]

Promising Discovery for a Non-Invasive Early Detection of Alzheimer’s Disease

(ScienceDaily) A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the Journal of Alzheimer's Disease (JAD), entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease." This paper has been highlighted as one of the most important contribution to this field. The paper stems from a fruitful … [Read More...]

CAREGIVER’S CORNER

Relaxation Techniques for Stress Relief

(HelpGuide.org) For many of us, relaxation means zoning out in front of the TV at the end of a stressful day. But this does little to reduce the damaging effects of stress. To effectively combat stress, we need to activate the body's natural relaxation response. You can do this by practicing relaxation techniques such as deep breathing, … [Read More...]

Caregiving: Dealing with the Strain on Your Marriage

(MayoClinic) Caregiving and marital strain often go hand in hand. Know the impact caregiving can have on your marriage and what you can do about it. Marriage isn't always easy. This can be especially true for those acting as a caregiver for a parent, in-law or other loved one with Alzheimer's. Understand how caregiving might affect your marriage … [Read More...]

Elder Orphans: How to Plan for Aging Without a Family Caregiver

(AARP) When you can't lean on family and friends to help take care of you, here's what you can do. Carol Marak was a caregiver for both her parents: Her mom had congestive heart failure and her dad had Parkinson's disease. After they died and she turned 60, she says, "It occurred to me ... oh, my goodness, I am not married. I do not have … [Read More...]

Participating in Activities You Enjoy—More Than Just Fun and Games

(NIH) There are many things you can do to help yourself age well: exercise and be physically active, make healthy food choices, and don’t smoke. But did you know that participating in activities you enjoy may also help support healthy aging? As people get older, they often find themselves spending more and more time at home alone. The isolation … [Read More...]

SCIENCE CORNER

Antibody Aducanumab Reduces Aβ Plaques in Alzheimer’s Disease

Nature. 2016 Sep 1;537(7618):50-6. doi: 10.1038/nature19323. The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Sevigny J1, Chiao P1, Bussière T1, Weinreb PH1, Williams L1, Maier M2, Dunstan R1, Salloway S3, Chen T1, Ling Y1, O'Gorman J1, Qian F1, Arastu M1, Li M1, Chollate … [Read More...]

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

Mayo Clin Proc. 2011 Sep;86(9):876-84. doi: 10.4065/mcp.2011.0252. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Ahlskog JE1, Geda YE, Graff-Radford NR, Petersen RC. Abstract A rapidly growing literature strongly suggests that exercise, … [Read More...]

Cognitive Function Improvements After Resistance Training in Older Adults with Mild Cognitive Impairment

J Am Geriatr Soc 2016.Version of Record online: 24 OCT 2016. DOI: 10.1111/jgs.14542 Mediation of Cognitive Function Improvements by Strength Gains After Resistance Training in Older Adults with Mild Cognitive Impairment: Outcomes of the Study of Mental and Resistance Training Yorgi Mavros PhD, … [Read More...]

Environmental Risk Factors for Dementia: a Systematic Review

BMC Geriatr. 2016 Oct 12;16(1):175. Environmental risk factors for dementia: a systematic review. Killin LO, Starr JM, Shiue IJ, Russ TC Abstract Background Dementia risk reduction is a major and growing public health priority. While certain modifiable risk factors for dementiahave been … [Read More...]